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anti tap 1  (Proteintech)


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    Structured Review

    Proteintech anti tap 1
    Anti Tap 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 47 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+tap+1/TAP1+Antibody/pm40680611-227-7-9
    Average 94 stars, based on 47 article reviews
    anti tap 1 - by Bioz Stars, 2026-10
    94/100 stars

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    Related Articles

    other:

    Article Title: Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation.
    Article Snippet: ERAP1 is an emerging target for a large subclass of severe autoimmune diseases known as “MHC-I-opathy”, together with tumor immunity.. Nevertheless, effective inhibitors targeting ERAP1 remain a challenge.. In this study, a novel food-derived natural product ERAP1-targeting inhibitor, carnosic acid, was identified, and to our knowledge, it is one of the best active compounds among the highly selective inhibitors targeting the orthosteric site of ERAP1.

    Article Title: Corilagin regulates antigen processing and presentation by directly binding to inhibit ERAP1.
    Article Snippet: ERAP1 is a critical aminopeptidase that acts as the final “editor” of endogenous antigen peptides in the endoplasmic reticulum, playing a key role in the MHC-I-mediated antigen processing and presentation pathway.. It has become a novel target for a broad class of severe autoimmune diseases, referred to as “MHC-I-opathy,” as well as for tumor immune evasion.. Here, we report the discovery of a food-derived natural product inhibitor, Corilagin, with a novel scaffold that directly interacts with ERAP1, identified through high-throughput screening.

    Western Blot:

    Article Title: STING agonist-based ER-targeting molecules boost antigen cross-presentation.
    Article Snippet: The following fluorescent conjugate-labeled antibodies were used: FITC-anti-CD11c (BioLegend, 117306); PE-anti-CD11b (BioLegend, 101207); APC/Cy7-anti-CD62L (BioLegend, 104427); PB-anti-CD44 (BioLegend, 156005); BV650-anti-CD127 (BioLegend, 135043); APC-antiCD24 (BioLegend, 138505); PerCP/Cy5.5-anti-CD172α (BioLegend, 144010) ; PE/Cy7-anti-B220 (BioLegend, 103222); PB-anti-CD86 (BioLegend,105007); BV421-anti-CD86 (BioLegend, 105032); APC-anti-H-2Kb-SIINFEKL (BioLegend, 141606); PE-anti-H2-Kb-SIINFEKL (1:100, BioLegend, 141603); PE/Cy7-anti-H-2Kb-SIINFEKL (BioLegend,141607); PE-anti-H2-Kb-SIINFEKL (BioLegend, 141603); PE-antiH-2Kb (BioLegend, 116508); APC/Cy7-anti-CD103 (BioLegend, 121431); FITC-anti-CD3 (BioLegend, 100203); BV711-anti-CD8a (BioLegend,100747); APC-anti-CD8a (BioLegend, 100712); PE-anti-CD8b.2 (BioLegend, 140408); PE-H-2D(b) MC38 Adpgk peptide tetramer (Helixgen, HG08T23002); PE-H-2k(b) OVA257-264 tetramer (Helixgen, HG08T14028); CFSE(BioLegend, 423801); PE-antiCD4 (BioLegend, 100408); APC-anti-IFN-γ (BioLegend, 505810); PE/Cy7-anti-IL-4 (BioLegend, 504117) 4. .. The following antibodies were used for Immunoblotting and immunodot-blotting: anti-STING (Cell Signaling Technology, 13647), anti-TBK1 (Cell Signaling Technology, 3504T), anti-pSTING (Cell Signaling Technology, 72971S), anti-pTBK1 (Cell Signaling Technology, 5483T), anti-GAPDH (Abbkine, ABL1020); streptavidin-HRP (Thermo scientific, 21130); anti-rat IgG, HRP-linked antibody (Cell Signaling Technology, 7077); anti-rabbit IgG, HRP-linked antibody (Cell Signaling Technology, 7074); anti-mouse IgG, HRP-linked antibody (Cell Signaling Technology, 7076); anti-calreticulin (Abcam, ab2907), anti-TAP-1 (Proteintech, 11114-1-AP), anti-proteasome 20S (Abcam, ab22673). .. The following antibodies or dyes are used for immunofluorescent imaging analysis: DAPI (Sigma Aldrich, D9542, 1:500), anti-FLAG (Sigma-Aldrich, F1804), anti-calreticulin (Abcam, ab2907), anti-TAP1 (Proteintech, 11114-1-AP), anti-proteasome 20S (Abcam, ab22673), anti-GM130 (BD, 610822), anti-STING (Sigma-Aldrich, MABF270), AF488-conjugated anti-mouse IgG (Cell Signaling Technology, 4408), AF555-conjugated anti-rabbit IgG (Abcam, ab150074), or AF647-conjugated Streptavidin (Bioss, bs-0437P-AF647), STAR-ORANGE anti-mouse IgG (Abberior, STORANGE-1001), and STAR- RED anti-rabbit IgG (Abberior, STRED-1002) 6.

    Article Title: STING agonist-based ER-targeting molecules boost antigen cross-presentation
    Article Snippet: The following fluorescent conjugate-labeled antibodies were used: FITC-anti-CD11c (BioLegend, 117306); PE-anti-CD11b (BioLegend, 101207); APC/Cy7-anti-CD62L (BioLegend, 104427); PB-anti-CD44 (BioLegend, 156005); BV650-anti-CD127 (BioLegend, 135043); APC-antiCD24 (BioLegend, 138505); PerCP/Cy5.5-anti-CD172α (BioLegend, 144010) ; PE/Cy7-anti-B220 (BioLegend, 103222); PB-anti-CD86 (BioLegend,105007); BV421-anti-CD86 (BioLegend, 105032); APC-anti-H-2Kb-SIINFEKL (BioLegend, 141606); PE-anti-H2-Kb-SIINFEKL (1:100, BioLegend, 141603); PE/Cy7-anti-H-2Kb-SIINFEKL (BioLegend,141607); PE-anti-H2-Kb-SIINFEKL (BioLegend, 141603); PE-antiH-2Kb (BioLegend, 116508); APC/Cy7-anti-CD103 (BioLegend, 121431); FITC-anti-CD3 (BioLegend, 100203); BV711-anti-CD8a (BioLegend,100747); APC-anti-CD8a (BioLegend, 100712); PE-anti-CD8b.2 (BioLegend, 140408); PE-H-2D(b) MC38 Adpgk peptide tetramer (Helixgen, HG08T23002); PE-H-2k(b) OVA257-264 tetramer (Helixgen, HG08T14028); CFSE(BioLegend, 423801); PE-antiCD4 (BioLegend, 100408); APC-anti-IFN-γ (BioLegend, 505810); PE/Cy7-anti-IL-4 (BioLegend, 504117) 4. .. The following antibodies were used for Immunoblotting and immunodot-blotting: anti-STING (Cell Signaling Technology, 13647), anti-TBK1 (Cell Signaling Technology, 3504T), anti-pSTING (Cell Signaling Technology, 72971S), anti-pTBK1 (Cell Signaling Technology, 5483T), anti-GAPDH (Abbkine, ABL1020); streptavidin-HRP (Thermo scientific, 21130); anti-rat IgG, HRP-linked antibody (Cell Signaling Technology, 7077); anti-rabbit IgG, HRP-linked antibody (Cell Signaling Technology, 7074); anti-mouse IgG, HRP-linked antibody (Cell Signaling Technology, 7076); anti-calreticulin (Abcam, ab2907), anti-TAP-1 (Proteintech, 11114-1-AP), anti-proteasome 20S (Abcam, ab22673). .. The following antibodies or dyes are used for immunofluorescent imaging analysis: DAPI (Sigma Aldrich, D9542, 1:500), anti-FLAG (Sigma-Aldrich, F1804), anti-calreticulin (Abcam, ab2907), anti-TAP1 (Proteintech, 11114-1-AP), anti-proteasome 20S (Abcam, ab22673), anti-GM130 (BD, 610822), anti-STING (Sigma-Aldrich, MABF270), AF488-conjugated anti-mouse IgG (Cell Signaling Technology, 4408), AF555-conjugated anti-rabbit IgG (Abcam, ab150074), or AF647-conjugated Streptavidin (Bioss, bs-0437P-AF647), STAR-ORANGE anti-mouse IgG (Abberior, STORANGE-1001), and STAR- RED anti-rabbit IgG (Abberior, STRED-1002) 6.



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    <t>TAP-1</t> protein levels and TAP1 gene expression stratified according to the severity of the cervical lesions, Asp697Gly SNP genotypes, chromosomal number, and HPV infection. Number of patients analyzed (N). The Mann-Whitney and Kruskal-Wallis tests were used to estimate the differences between the expressions of TAP-1 protein and TAP1 mRNA in the evaluated groups. TAP-1 protein expression (A–D) in cervical biopsies, and TAP1 gene expression (E–H) in cervical exfoliative samples.
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    Image Search Results


    TAP-1 protein levels and TAP1 gene expression stratified according to the severity of the cervical lesions, Asp697Gly SNP genotypes, chromosomal number, and HPV infection. Number of patients analyzed (N). The Mann-Whitney and Kruskal-Wallis tests were used to estimate the differences between the expressions of TAP-1 protein and TAP1 mRNA in the evaluated groups. TAP-1 protein expression (A–D) in cervical biopsies, and TAP1 gene expression (E–H) in cervical exfoliative samples.

    Journal: Frontiers in Cellular and Infection Microbiology

    Article Title: The antigen processing-associated transporter gene polymorphism: Role on gene and protein expression in HPV-infected pre-cancerous cervical lesion

    doi: 10.3389/fcimb.2022.979800

    Figure Lengend Snippet: TAP-1 protein levels and TAP1 gene expression stratified according to the severity of the cervical lesions, Asp697Gly SNP genotypes, chromosomal number, and HPV infection. Number of patients analyzed (N). The Mann-Whitney and Kruskal-Wallis tests were used to estimate the differences between the expressions of TAP-1 protein and TAP1 mRNA in the evaluated groups. TAP-1 protein expression (A–D) in cervical biopsies, and TAP1 gene expression (E–H) in cervical exfoliative samples.

    Article Snippet: After the inactivation of endogenous peroxidase by the peroxidase-blocking reagent, the slides were incubated in a humid chamber, at room temperature, with the following primary antibodies: rabbit polyclonal anti-TAP-1 (ab83817; Abcam, Cambridge, UK) and rabbit polyclonal anti-TAP-2 (ab180611; Abcam).

    Techniques: Expressing, Infection, MANN-WHITNEY